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Eagles vs. Titans: Kickoff Time, Odds, Injuries and Matchups to Watch

Summary: This guide covers the essentials for Philadelphia's Week 2 visit to Tennessee — kickoff time, TV and streaming options, the betting line, the injury report, and the roster battles likely to decide the game.

The Tennessee Titans host the Philadelphia Eagles on Sunday, Sept. 20, 2026, at Nissan Stadium in Nashville. Kickoff is set for 1 p.m. ET on FOX, with streaming available through the FOX Sports app and FOXSports.com.

Both teams arrive from very different Week 1 outcomes. The Eagles edged the Washington Commanders at home, 24-22. The Titans, meanwhile, struggled in a 23-10 home loss to the New York Jets. Quarterback Cam Ward completed only 59.4 percent of his passes for 140 yards, and the offense never found a rhythm.

Philadelphia enters as a 7-point road favorite, with the over/under set at 39.5 points. That line reflects a matchup the Eagles should control up front. Tennessee allowed Jets running back Breece Hall to rush for more than 100 yards in Week 1, which bodes well for Saquon Barkley. If Philadelphia can establish the run early, the passing game should open up.

But the Eagles have their own concern. Their offensive line allowed three sacks and multiple pressures against Washington, and Tennessee's pass rush could test that unit again. On the other side of the ball, Philadelphia's secondary offers a significant edge. The outside corner combo of Quinyon Mitchell and Riq Woolen creates real problems for Tennessee's receivers. Defensive back Cooper DeJean was banged up in Week 1 and sat out practice Wednesday, leaving his status worth monitoring.

The final injury report lists Titans pass rusher Jonathan Greenard as out and defensive back Andrew Mukuba as questionable. Those absences thin Tennessee's defense against a Philadelphia offense looking to go 2-0.

Road success has defined this Eagles team under head coach Nick Sirianni. Since he took over in 2021, Philadelphia holds a 30-13 record away from home, the best road mark in the NFL over that span. Sunday also marks the Eagles' first trip to Nashville since 2018, and a large contingent of Philadelphia fans is expected to travel.

One other factor could shift the game: the weather. The projected feels-like temperature at kickoff is 94 degrees Fahrenheit. That heat could matter for both offensive lines and for a Titans defense trying to keep the game close.

A win for Tennessee would pull them to 1-1 and stabilize a season that started poorly. For Philadelphia, a road victory would confirm the team's early momentum and extend its impressive away record.

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